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changing to another univerity after deferring
If she wants to re-apply through UCAS she will need to give up her deferred offer and start again.
It is not possible to start a fresh UCAS application whilst holding an offer.
She should think carefully about her reasons for changing her mind. There is an inherent risk in her plan, so it is necessary to be very careful.
We have some advice on applications here:
I hope this is useful advice, good luck!