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PhD/MPhil Cell Matrix Research

University of Manchester

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Course options

  • Qualification

    PhD/DPhil - Doctor of Philosophy

  • Location

    The University of Manchester

  • Study mode

    Full time

  • Start date

    SEP-21

  • Duration

    3 years

Course summary

Programme description

Our PhD/MPhil Cell Matrix Research programme enables you to undertake a research project that will improve understanding of the interactions between cells and their extracellular matrix environment in the contexts of health, disease and tissue regeneration.

Cells continuously sense, synthesise and remodel the proteins and glycosaminoglycans that form the Extracellular Matrix (ECM). This matrix varies in its biochemical and biophysical properties in different parts of the body, and their responses to these differences influence the motility, growth, differentiation and survival of cells. Therefore, cell-matrix interactions underpin the development of multicellular organisms and are essential throughout the life of an organism.

Aberrations in cell-matrix communication are associated with severe diseases, such as cancer, fibrosis, cardiovascular disease, and inflammatory disorders. Conversely, the synthesis of healthy matrix can be used to induce new functional tissue that can support regeneration. Because understanding how cells sense and synthesise their ECM is critically important for preventing disease and supporting tissue regeneration, our Cell Matrix postgraduate research programme comprises projects that study:

  • the biochemistry and biophysical properties of the ECM;
  • the mechanisms of how cells interact with the matrix and how they translate the extracellular information into a cellular response;
  • how cell-matrix interactions affect cell fate and tissue function;
  • the mechanisms of how cells synthesise and remodel their ECM environment, including how aberrant signals affect health and can result in disease;
  • how ECM signalling can be applied to tissue regeneration.

Career opportunities

Your postgraduate research degree will open up a range of career opportunities after you graduate.

Tuition fees

Students living in United States
(international fees)

Information not available

Please check with the institution for most up to date details.

University information

University of Manchester

  • University League Table

    17th

  • Campus address

    The University of Manchester, Oxford Road, Manchester, Manchester, M13 9PL, England

Subject rankings

  • Subject ranking

    17th out of 103 2

    6th out of 110 6

    19th out of 72 3

  • Entry standards

    / Max 240
    170 74%

    13th

    3
  • Graduate prospects

    / Max 100
    79 79%

    17th

  • Student satisfaction

    / Max 5
    4.03 81%

    56th

    5
  • Entry standards

    / Max 236
    210 88%

    4th

    9
  • Graduate prospects

    / Max 100
    87 87%

    36th

  • Student satisfaction

    / Max 5
    4.06 81%

    26th

    14
  • Entry standards

    / Max 236
    177 75%

    14th

  • Graduate prospects

    / Max 100
    78 78%

    34th

    1
  • Student satisfaction

    / Max 5
    4.07 81%

    38th

    12

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