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Course options

  • Qualification

    PhD/DPhil - Doctor of Philosophy

  • Location

    The University of Manchester

  • Study mode

    Full time

  • Start date

    SEP-21

  • Duration

    3 years

Course summary

Programme description

Our PhD/MPhil Pharmacology programme enables you to undertake a research project that will improve understanding of Pharmacology.

Our pharmacology research focuses on a range of topics. These include:

  • the pharmacology of drug efflux transporters, particularly ABCB1 P-glycoprotein, ABCG2 breast cancer resistance protein and ABCC multidrug resistance-associated transporters;
  • developing complex, physiologically-relevant in vitro cell systems to investigate transport, metabolism and delivery of therapeutic drugs;
  • understanding the pharmacological and molecular mechanisms that regulate expression and function of drug efflux transporters, particularly in the blood-brain barrier;
  • the role of blood-brain barrier drug efflux transporters in drug delivery to the central nervous system and the effects of inflammatory and degenerative conditions, eg Alzheimer's disease, on efflux transporter function;
  • the biological role of lipid networks in health and disease, particularly their roles in inflammation, cellular communications and tissue responses;
  • employing mass spectrometry-based lipidomic technology, in conjunction with functional, metabolic and signaling approaches to characterise lipid profiles in physiological and pathophysiological conditions;
  • investigating the role of lipids in skin homeostasis and in response to inflammation, injury and wound healing;
  • studying role of local hormones in diseases and conditions associated with the female reproductive tract (eg dysmenorrhoea, endometriosis and the detection and prevention of preterm labour);
  • molecularly identifying and pharmacologically characterising receptors expressed in the female reproductive system;
  • understanding the physiological and pharmacological characteristics of the placenta. These studies include the development of placental homing peptide-microRNA inhibitor conjugates for targeted enhancement of placental growth signaling.

Teaching and learning

PhD/MPhil programmes are based on individual research projects that last three to four years (PhD) or one year (MPhil), working with a specific Primary Supervisor and Co-Supervisor(s).

Applicants are specifically matched with a Primary Supervisor and individual project based on their research interests and background.

Career opportunities

Your postgraduate research degree will open up a range of career opportunities after you graduate.

Tuition fees

Students living in United States
(international fees)

Information not available

Please check with the institution for most up to date details.

University information

University of Manchester

  • University League Table

    17th

  • Campus address

    The University of Manchester, Oxford Road, Manchester, Manchester, M13 9PL, England

Subject rankings

  • Subject ranking

    11th out of 46 1

  • Entry standards

    / Max 222
    154 67%

    15th

    2
  • Graduate prospects

    / Max 100
    95 95%

    19th

  • Student satisfaction

    / Max 5
    4.12 82%

    21st

    9

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